Glycobiology and Medicine

The potential for glycobiology to improve the practice of medicine has been well
recognised, which is why biannual meetings concerning the association have been
taking place for the last 14 years. The science of glycobiology has matured rapidly,
and with it the far reaching clinical implications are becoming understood. The next
decade is going to see this final frontier of science conquered. The impact this
understanding of glycobiology will have upon our practice of medicine is going to
be exciting. The 7th Jenner Glycobiology and Medicine Symposium was designed
to reflect these advances. All the major clinical areas were involved, with contributions
from pivotal players in science and medicine.

Includes supplementary material: sn.pub/extras

1. Glycosylation: Disease Targets and Therapy, Zitzmann et al.; 2. Long Alkylchain Iminosugars Block the HCV P7 Ion Channel, Pavlovic et al.; 3. The Bovine Viral Diarrhoea Virus: A Model for the Study of Antiviral Molecules Interfering with N-Glycosylation and Folding of Envelope Glycoprotein, Durantel et al.; 4. Antibody Recognition of a Carbohydrate Epitope: A Template for HIV Vaccine Design, Scanlan et al. ; 5. Interaction of Schistosome Glycans with the Host Immune System, Van Die et al.; 6. The Mannan-Binding Lectin (MBL) of Complement Activation: Biochemistry, Biology and Clinical Implications, Jensenius et al.; 7. Killer Cell Lectin-like Receptors and the Natural Killer Cell Gene Complex, Nylenna et al. ; 8. Glycosylation Influences the Ligand Binding Activities of Mannose Receptor, Roc Su et al. ; 9. Human Immunoglobulin Glycosylation and the Lectin Pathway of Complement Activation, Arnold et al.; 10. Gelatinase B Participates in Collagen II Degradation and Releases Glycosylated Remnant Epitopes in Rheumatoid Arthritis, Van den Steen et al.; 11. Hyaluronan in Immune Processes, Alan J. Wright and Anthony J. Day; 12. Glycosylation and the Function of the T Cell Co-receptor CD8, Shore et al.; 13. Immunogenecity of Calreticulin-bound Murine Leukemia Virus Glycoprotein, Mimura et al.; 14. Glycosylation and GPI Anchorage of the Prion Protein, Nigel Hooper; 15. Glycosylation Defects and Muscular Dystrophy, Blake et al.; 16. Roles of Complex and Hybrid N-Glycans and O-Fucose Glycans in Oocyte Development and Function, Shi et al.; 17. Mucin Oligosaccharides and Pigeon Fanciers Lung, Baldwin et al.; 18. Differential Glycosylation of Gelatinase B from Neutrophils and Breast Cancer Cells, Fry et al.; 19. Detection of Glycosylation Changes in Serum and Tissue Proteins in Cancer by Lectin Blotting, Ferguson et al.; 20. Carbohydrates and Biology of Staphylococcal Infections, Tarkowski et al.; 21. New Developments in Treating Glycosphingolipid Storage Diseases, Platt et al. ; 23. New Insights into Rheumatoid Arthritis Associated Glycosylation Changes, Alavi et al.; 24. Production of Complex Human Glycoproteins in Yeast, Tillman Gerngross; 25. Relationship Between the N-glycan Structures and Biological Activitities of Recombinant Human Erythropoietins Produced Using Different Culture Conditions and Purification Procedures, Yuen et al.; 26. Glycosylation of Natural and Recombinant Antibody Molecules, Roy Jefferis.