Firestein & Kelley’s Textbook of Rheumatology, 2-Volume Set
Beschreibung:
Dr. Firestein is the recipient of many awards and honors, including the Arthritis Foundation's Jane Wyman Humanitarian Award in 2010 for his contributions to rheumatology; the Arthritis Foundation Lee C. Howley Sr. Prize for Arthritis Research; and the American College of Rheumatology Distinguished Investigator Award. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians. He has served as an editor for the Textbook of Rheumatology for since the 7th edition (2004).Iain McInnes is Director of the Institute of Infection, Immunity and Inflammation at the University of Glasgow, UK. He has extensive experience in leading multicenter programs nationally and internationally. He is Director of the Scottish MRC Clinical Pharmacology and Pathology Clinical PhD Training Program, Chief Investigator for the Scottish Early RA Cohort (SERA) and the related SMS-IC biomarker discovery program (PROMISERA), and chief investigator of numerous global phase II and III clinical trials of novel immune therapies. He has served as member or chair of numerous national grant-funding panels and as chair of several European League Against Rheumatism (EULAR) scientific committees - he is now Treasurer and President Elect of EULAR serving on its Steering Committee. He is formerly Chairman of the Foundation for European Rheumatology Research (Foreum) Scientific Committee and leads the EULAR-supported European Roadmap Program that is defining the research agenda for rheumatology for the next decade.James R. O'Dell, MD is the Stokes Shackleford Professor of Internal Medicine, Vice-Chairman of Internal Medicine and Chief of the Division of Rheumatology at the University of Nebraska Medical Center (UNMC) in Omaha. Dr. O'Dell founded and has directed the Rheumatoid Arthritis Investigational Network (RAIN) for the last 25 years. Dr. O'Dell is the PI of the large multinational RA research study based at the VA through their cooperative studies program. Dr. O'Dell has published extensively, mostly in the area of rheumatoid arthritis. He has presented frequently at national and international meetings and has more than 100 published articles in top-level rheumatology journals. He has served on numerous American College of Rheumatology (ACR) committees over the last 20 years, including time on both the ACR and REF BOD, as well as a two-year term as President of the Research and Education Foundation of the ACR and was President of the College (2011-2012). Additionally, he is Editor-in-Chief of Up To Date for Rheumatology.Gary Koretzky, MD, PhD is Professor of Medicine at Weill Cornell Graduate School. Dr. Koretzky's research aims to better understand the signal transduction events that occur following engagement of the T cell antigen receptor. He has been continuously funded by the National Institutes of Health since establishing his independent research group, as the laboratory has expanded its interests to study more globally the molecular events important for immune cell development, differentiation and function. Dr. Koretzky has published more than 200 research articles. He is a past President of the American Society of Clinical Investigation (2000) and Councilor of the Association of American Physicians (2008-2012), is a Fellow of the American Association for the Advancement of Science (2004), a member of the Institute of Medicine of the National Academies (2008), a Fellow of the American Academy of Arts & Sciences (2012) and serves as the Editor-in-Chief of Immunological Reviews (2002-present).
Through 10 outstanding editions, Kelley & Firestein's Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference.
- Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes-including key data on therapeutic outcomes to better inform clinical decision making.
- Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis.
- Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs.
- Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology.
- Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
VOLUME I
Part 1: Structure and Function of Bone, Joints, and Connective Tissue
1. Biology of the Normal Joint, 1 Carla R. Scanzello and Steven R. Goldring
2. Synovium, 20 Douglas J. Veale and Gary S. Firestein
3. Cartilage and Chondrocytes, 34 Ali Mobasheri, Mary B. Goldring, and Richard F. Loeser
4. Biology, Physiology, and Morphology of Bone, 60 Aline Bozec, Anika Grüneboom, and Georg Schett
5. Muscle: Anatomy, Physiology, and Biochemistry, 67 Mark S. Miller, Edward P. Debold, and Michael J. Toth
6. Biomechanics, 80 Kenton R. Kaufman and KaiNan An
7. Regenerative Medicine and Tissue Engineering, 92 Frank P. Luyten, Cosimo De Bari, and Francesco Dell'Accio
8. Proteinases and Matrix Degradation, 109 Yoshifumi Itoh
Part 2: Cells Involved in Autoimmune Diseases and Inflammation
9. Dendritic Cells, 132 Mansi Saxena, Nicolas Vabret, Luciana Ribeiro Muniz, and Nina Bhardwaj
10. Mononuclear Phagocytes, 149 Deborah R. Winter, Anna Montgomery, and Harris Perlman
11. Neutrophils, 161 Binita Shah, Nathalie Burg, and Michael H. Pillinger
12. T Lymphocytes, 182 Ralph C. Budd
13. B Cells, 199 Yong-Rui Zou, Christine Grimaldi, and Betty Diamond
14. Fibroblasts and Fibroblast-like Synoviocytes, 222 Christopher D. Buckley and Andrew Filer
15. Mast Cells, 241 Peter A. Nigrovic
16. Innate Lymphoid Cells and Natural Killer Cells, 254 Michael A. Paley and Wayne M. Yokoyama
17. Platelets and Megakaryocytes, 262 Eric Boilard and Peter A. Nigrovic
Part 3: Effector Mechanisms in Autoimmunity and Inflammation
18. Principles of Signaling, 273 Abel Suarez-Fueyo, Vaishali R. Moulton, and George C. Tsokos
19. The Immunologic Repercussions of Cell Death, 286 Helen M. Beere and Douglas R. Green
20. Innate Immunity, 306 Gregoire Lauvau and Steven A. Porcelli
21. Adaptive Immunity, 320 Martha S. Jordan and Gary A. Koretzky
22. Autoimmunity and Tolerance, 337 Dwight H. Kono and Argyrios N. Theofilopoulos
23. The Microbiome in Health and Disease, 355 Rob Knight
24. Metabolic Regulation of Immunity, 368 Ruoning Wang, Tingting Wang, and Stephen Tait
25. Genetics of Rheumatic Diseases, 378 Stephen Eyre and Anne Barton
26. Epigenetics of Rheumatic Diseases, 393 Amr H. Sawalha and Matlock A. Jeffries
27. Complement System, 409 V. Michael Holers and Leendert A. Trouw
28. Prostaglandins, Leukotrienes, and Related Compounds, 420 Robert B. Zurier
29. Chemokines and Cellular Recruitment, 437 Gerard Graham
30. Angiogenesis, 445 Ursula Fearon, Zoltán Szekanecz, and Douglas J. Veale
31. Cytokines, 455 Iain B. McInnes
32. Experimental Models for Rheumatoid Arthritis, 467 Rikard Holmdahl
33. Neuronal Regulation of Pain and Inflammation, 480 Camilla I. Svensson and Linda S. Sorkin
Part 4: Broad Issues in the Approach to Rheumatic Disease
34. Clinical Research Methods in Rheumatic Disease, 495 Jeffrey R. Curtis, Yvonne M. Golightly, and Kenneth G. Saag
35. Economic Impact of Arthritis and Rheumatic Conditions, 510 Louise B. Murphy
36. Assessment of Health Outcomes, 522 Dorcas E. Beaton, Maarten Boers, Peter Tugwell, and Lara Maxwell
37. Biomarkers in Rheumatology, 536 Michael J. Townsend, Saloumeh K. Fischer, and Andrew C. Chan
38. Occupa