Volpe’s Neurology of the Newborn

Volpe’s Neurology of the Newborn
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Joseph J. (Bronson Crothers Professor of Neurology Volpe
3550 g
282x224x53 mm

Joseph Volpe is generally considered to have founded the field of neonatal neurology.
Dr. Inder is a dual-boarded neonatologist and child neurologist and is the current Chair of the Department of Pediatric Newborn Medicine. A native of New Zealand, she previously worked at the University of Melbourne, and Washington University in St. Louis before joining Brigham and Women's Hospital in 2013. She has a passion for improving long-term outcomes of high-risk infants including premature infants and at-risk term born infants. Dr. Inder is the Mary Ellen Avery Professor of Pediatrics in the Field of Newborn Medicine at Harvard Medical School.

Dr. Basil T. Darras is Associate Neurologist-in-Chief and Chief of the Division of Clinical Neurology at Boston Children's Hospital, and the Joseph J. Volpe Professor of Neurology at Harvard Medical School. Dr. Darras is a pediatric neurologist with advanced training and certification in human genetics and neuromuscular medicine. At Boston Children's he serves as Director of the Neuromuscular Program, which includes one of the oldest and most active muscular dystrophy clinics in the country and where he specializes in the care of children with neuromuscular conditions originating from inherited or acquired conditions of the motor unit. He has published over 140 original reports in peer-reviewed journals and over 70 chapters, reviews and editorials; his major publications and specific research interests have focused on the molecular genetics, diagnostics, and therapeutics of Duchenne and Becker muscular dystrophies and spinal muscular atrophy, and on defining the indications for new diagnostic methodologies in the evaluation of children with pediatric neuromuscular diseases. Basic research, carried out in collaboration with scientists in the research laboratories of Boston Children's and other institutions, focuses on the description of novel mutations in patients with neuromuscular diseases and the application of new technologies to explore the pathogenesis and treatment of congenital myopathies and muscular dystrophies. Dr. Darras is site PI for the consortium conducting Pediatric Neuromuscular Clinical Research in Spinal Muscular Atrophy, and site PI/PD for the NeuroNEXT NINDS Program. He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy.

Linda de Vries is a neonatologist and pediatric neurologist, and obtained her PhD degree in Utrecht (1987). Since 1989, she has worked in the department of Neonatology in the University Medical Center Utrecht, where she is a professor in Neonatal Neurology. Her research focuses on prediction of neurodevelopmental outcome in high risk preterm and full-term newborns, using neurophysiology and neuro-imaging methods. These at risk children are also seen by her in the follow-up clinic until early childhood. She has a special interest in neonatal stroke and brain plasticity. Her work has been published in >400 publications.
The 5th edition of this indispensable resource captures the latest insights in neonatal neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has completely revised his masterwork from cover to cover, describing everything from the most up-to-the-minute discoveries in genetics through the latest advances in the diagnosis and management of neurologic disorders. He delivers all the clinical guidance you need to provide today's most effective care for neonates with neurological conditions.
Unit I: Human Brain Development


1. Neural Tube Development and Defects

2. Prosencephalic Development and Defects

3. Congenital Hydrocephalus

4. Cerebellar Development and Defects

5. Neuronal Proliferative Events and Defects

6. Neuronal Migrational Events and Defects

7. Organizational Events and Defects

8. Myelination Events and Defects

Unit II: Neurological Evaluation


9. Neurological Examination: Normal and Abnormal Features

10. Specialized Neurological Studies

11. Neurodevelopmental Followup

Unit III: Neonatal Seizures


12. Neonatal Seizures

Unit IV: Hypoxic-ischemic and Related Disorders


13. Pathophysiology General Principles

14. Encephalopathy of the Preterm - Neuropathology

15. Encephalopathy of the Preterm - Pathophysiology

16. Encephalopathy of the Preterm - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy

17. Intrauterine, Intrapartum Assessments in the Term Infant

18. Hypoxic Ischemic Injury in the Term Infant - Neuropathology

19. Hypoxic Ischemic Injury in the Term Infant - Pathophysiology

20. Hypoxic Ischemic Injury in the Term Infant - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy

21. Stroke in the Newborn

Unit V: Intracranial Hemorrhage


22. Intracranial/Hemorrhage - Supratentorial (Subdural, Subarachnoid, Intraventricular (Term Infant), Miscellaneous

23. Intracranial Hemorrhage Infratentorial/Cerebellar

24. Preterm IVH/Posthemorrhagic Hydrocephalus

Unit VI: Metabolic Encephalopathies


25. Glucose

26. Bilirubin

27. Amino acids

28. Organic acids

Unit VII: Degenerative Disorders

29. Degenerative Disorders of the Newborn

Unit VIII: Neuromuscular Disorders


30. Evaluation, Specialized Studies

31. Arthrogryposis Multiplex Congenita

32. Levels Above Lower Motor Neuron to Neuromuscular Junction

33. Muscle Involvement and Restricted Disorders

Unit IX: Intracranial Infections


34. Viral, Protozoan and Related Intracranial Infections

35. Bacterial and Fungal Intracranial Infections

Unit X: Perinatal Trauma

36. Injuries of Extracranial, Cranial, Intracranial, Spinal Cord and Peripheral Nervous System Structures

Unit XI: Intracranial Mass Lesions

37. Brain Tumors and Vein of Galen Malformations

Unit XII: Drugs and the Developing Nervous System


38. Passive Addiction and Teratogenic Effects

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