Models of Cellular Regulation

Baltazar Aguda is currently associate professor of Genetics & Genomics at the Boston UniversitySchool of Medicine. He holds joint appointments in Biomedical Engineering, in the Bioinformatics& Systems Biology program at Boston University, and a membership in the Center for Biodynamicsin the same university. Recently, he was appointed member of the National ScienceFoundation's (NSF, USA) research proposal review panel in molecular & cellular biosciences(2004-7). He was a visiting faculty at the Mathematical Biosciences Institute at Ohio State University(2003), at the Weizmann Institute of Science in Israel (2000), and a visiting associate atthe California Institute of Technology (2000-2001). Dr. Aguda obtained his PhD in Chemistry(Chemical Physics Program) from the University of Alberta in Canada (1986), and was a tenuredfaculty member of the Department of Chemistry & Biochemistry at Laurentian University inCanada (1994-2002) before moving to Boston.Avner Friedman is a Distinguished Professor of Mathematics and Physical Sciences atthe Ohio State University, where he also serves as the Director of the Mathematical BiosciencesInstitute. He received his Ph.D. degree in 1956 from the Hebrew University.He was Professor of Mathematics at Northwestern University (1962-1985), and a DuncanDistinguished Professor of Mathematics at Purdue University (1985-1987).

This book illustrates the mechanisms and models linking the realms of molecular interactions and biological processes or functions. It addresses the need of mathematical modelers to learn how to formulate models of cellular processes and to understand how quantitative modeling can help sort through the complexities of molecular regulatory networks.

1: General Introduction