Genomic and Precision Medicine

Dr. Ginsburg is the founding Director of the Center for Applied Genomics & Precision Medicine in the Duke Institute for Genome Sciences & Policy. He is also Professor of Medicine and of Pathology at Duke University Medical Center, Professor of Biomedical Engineering at Duke Pratt School of Engineering, and Co-Director of the Duke Translational Medicine Institute.Huntington Willard is on the faculty of the Department of Human Genetics at the University of Chicago. Prior to this appointment, Willard was the President and Director of the Marine Biological Laboratory and Professor of Human Genetics at the University of Chicago. He was previously on the faculty at Duke University, where he was founding director of the university-wide Duke Institute for Genome Sciences & Policy from 2003 to 2014, the Nanaline H. Duke Professor of Genome Sciences, and the Arts & Sciences Professor of Biology & Genome Sciences.John Strickler is Associate Professor in the Department of Medicine, Division of Medical Oncology at Duke University Medical Center, Durham, NC, USA.Matthew Stuart McKinney is Assistant Professor of Medicine in the Department of Medicine, Hematologic Malignancies and Cellular Therapy, Duke University Medical Center, Durham, NC, USA.

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field.

1. Overview: The Cancer Genome Landscape
2. Application of Human Genome Information to Clinical Practice
3. Translating genome information into clinical practice and human health
4. Big Data and Translational Bioinformatics Genomic and Personalized Medicine
5. Health Risk Assessment and Family History
6. Clinical Decision Support
7. Overview of Policy, Ethical and Social Considerations
8. Lymphomas
9. Leukemias
10. Genomics of Lung Cancer
11. Breast Cancer
12. Ovarian Cancer
13. Colorectal Cancer
14. Prostate Cancer
15. Head and Neck Cancer
16. Brain Tumors and Gliomas
17. Melanoma
18. Metastatic Cancer
19. Bioinformatics and Personalized Cancer Care
20. Diagnostic-Therapeutic Combinations
21. Treatment Decisions and Cancer Mutations
22. Case Studies