In Situ Molecular Pathology and Co-Expression Analyses
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In Situ Molecular Pathology and Co-Expression Analyses

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ISBN-13:
9780124159440
Einband:
Buch
Erscheinungsdatum:
01.04.2013
Seiten:
289
Autor:
Gerard J. Nuovo
Gewicht:
1216 g
Format:
284x220x25 mm
Sprache:
Englisch
Beschreibung:

Gerard Nuovo received his MD from the University of Vermont College of Medicine in 1983. He did his training in Anatomic Pathology at Columbia Prebyterian College of Physicians and Surgeons in NYC. He then did a two year fellowship at Columbia Presbyterian in Molecular Virology and Gynecologic Pathology under the mentorship of Drs. Saul Silverstein, Chris Crum, and Ralph Richart. Dr. Nuovo's career has been dedicated to bridging the areas of surgical pathology and molecular pathology. He has published over 310 peer review papers in the field and written several textbooks in both Anatomic Pathology and Molecular Pathology. This textbook fulfills a strong ambition of Dr. Nuovo; to empower the next generation of researchers and diagnosticians to include in situ molecular pathology in their work by using easy-to-follow and easy-to-understand protocols for in situ hybridization, immunohistochemistry, and co-expression analyses.
This new laboratory reference manual will explain, in easy-to-understand language, simplified ways to understand and perform in situ hybridization and immunohistochemistry tests. The book will also focus much attention on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses.The fields of in situ hybridization and immunohistochemistry have expanded rapidly where computer-based analyses systems have greatly expanded the power of these methods. The automated platforms require that researchers and diagnostic biomedical investigators have a good understanding of the basics of in situ based tests, protocols and regimens for troubleshooting to maximize the use of these platforms.Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this clear presentation of protocols and theoretical framework. Data derived from in situ hybridization and immunohistochemistry, especially with computer-based co-expression analyses, offer a large advantage to researchers competing for federal moneys or private grants.

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