Constitutive Activity in Receptors and Other Proteins, Part a

Constitutive Activity in Receptors and Other Proteins, Part a
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Volume 484
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This volume of Methods in Enzymology covers the current methodology for the detection and assessment of constitutively active proteins. The chapters written by expert authors who are leaders in the field, provide hints and tricks not available in primary research publications.It is extensively referenced, with useful figures and tables throughout the volume.

Section I-- Identification and Measurement of Constitutive Activity

  1. Constitutive activity at the cannabinoid CB1 receptor and behavioral responses
  2. Katherine E. Hanlon and Todd W. Vanderah

  3. Detecting constitutive activity and protean agonism at the cannabinoid-2 receptor.
  4. Massimiliano Beltramo, Rossella Brusa, Isabella Mancini, Paola Scandroglio, Massimiliano. Beltramo

  5. Modulation of constitutive activity of the ghrelin receptor by use of pharmacological tools as well as mutagenesis
  6. Birgitte Holst and Jacek Mokrosinski

  7. Assessment of constitutive activity and internalization of GPR54 (Kiss1-r).
  8. Macarena Pampillo and Andy Videsh Babwah

  9. Assessment of Constitutive Activity in EP Prostanoid Receptors
  10. Hiromichi Fujino, Toshihiko Murayama, and John W. Regan

  11. a1D-Adrenergic receptors: constitutive activity and reduced expression at the plasma membrane
  12. J Adolfo Garcia-Sáinz, M. Teresa Romero-Ávila and Luz del Carmen Medina

  13. Constitutive activity of the histamine H1 receptor
  14. Saskia Nijmeijer, Rob Leurs and Henry F Vischer

  15. Constitutive activity of somatostatin receptor subtypes
  16. Anat Ben-Shlomo, Kolja Wawrowsky and Shlomo Melmed

  17. Assessment of homologous internalization of constitutively active N111G mutant of AT1 receptor
  18. Mohiuddin Ahmed Bhuiyan and Takafumi Nagatomo

  19. Methods to detect cell surface expression and constitutive activity of GPR6
  20. Balakrishna M. Prasad, Bettye Hollins and Nevin A. Lambert

  21. ß3-adrenoceptor agonists and (antagonists as) inverse agonists: history, perspective, constitutive activity and stereospecific binding.
  22. Maria Grazia Perrone and Antonio Scilimati

  23. Constitutive Activity of the Lutropin Receptor and its Allosteric Modulation by Receptor Heterodimerization
  24. Deborah L. Segaloff

  25. Assessing Constitutive Activity of Extracellular Calcium-Sensing Receptors in Vitro and in Bone
  26. Wenhan Chang, Melita Dvorak, and Dolores Shoback

  27. Constitutive Activity of Neural Melanocortin Receptors.
  28. Ya-Xiong Tao, Hui Huang, Zhi-Qiang Wang, Fan Yang, Jessica N. Williams, and Gregory V. Nikiforovich

  29. Measurement of Constitutive Activity of BMP Type I receptors
  30. Peter ten Dijke

  31. Probing the CA among dopamine D1 and D5 receptors and their mutants
  32. Bianca Plouffe, Jean-Philippe D'Aoust, Vincent Laquerre, Binhui Liang and Mario Tiberi

  33. Identification of Gain-of-Function Variants of the Human Prolactin Receptor
  34. Vincent Goffin, Roman L. Bogorad, and Philippe Touraine

  35. Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein (BMP) Type I Receptor that Causes Fibrodysplasia Ossificans Progressiva
  36. Frederick. Kaplan, Petra Seemann, Julia Haupt, Meiqi Xu, Vitali Lounev, Mary Mullins, Eileen M. Shore

  37. Identification and evaluation of constitutively active thyroid stimulating hormone receptor mutations
  38. Joaquin Lado-Abeal, Leah R. Quisenberry, and Isabel Castro-Piedras

  39. Assessment of constitutive activity of a G protein-coupled receptor, Cpr2, in Cryptococcus neoformans by heterologous and homologous methods
  40. Chaoyang Xue, Yina Wang, and Yen-Ping Hsueh

  41. In vitro and in vivo assessment of mu opioid receptor constitutive activity.
  42. Edward J. Bilsky, Denise Giuvelis, Melissa D. Osborn, Christina M. Dersch, Heng Xu and Richard B. Rothman

  43. Constitutively active µ-opioid methods
  44. Mark. Connor and John Traynor

  45. Protein Kinase Ck2 is a Constitutively-Active Enzyme That Promotes Cell Survival: Strategies To Identify Ck2 Substrates and Manipulate Its Activity In Mammalian Cells
  46. Jacob P. Turowec, James S. Duncan, Ashley C. French, Laszlo Gyenis, Ni

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