Primer to The Immune Response

Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating "e;Immunomovie"e;? that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles. Over 200 elegant 2-4 color illustrations 36 full-color plates of basic and clinical items of interest Take-home message and "e;Did You Get It?? self-test quiz at the end of each chapter 6 Appendices that provide topic enrichment 60-minute "e;Immunomovie"e;? illustrating the immune response to bacterial, viral and parasitic infections

Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating "e;Immunomovie"e;? that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles. Over 200 elegant 2-4 color illustrations 36 full-color plates of basic and clinical items of interest Take-home message and "e;Did You Get It?? self-test quiz at the end of each chapter 6 Appendices that provide topic enrichment 60-minute "e;Immunomovie"e;? illustrating the immune response to bacterial, viral and parasitic infections

1;Front cover;12;Primer to The Immune Response;43;Copyright page;54;Preface to the Text;65;Preface to the Immunomovie;86;Biographies;107;Acknowledgments;128;Table of contents;149;PART I: BASIC IMMUNOLOGY;209.1;Chapter 1: Introduction to the Immune Response;229.1.1;A. Historical Orientation;239.1.2;B. The Nature of the Immune Response;239.1.3;C. Types of Immune Responses: Innate and Adaptive;259.1.4;D. Interplay between the Innate and Adaptive Responses;309.1.5;E. Clinical Immunology;319.2;Chapter 2: Components of the Immune System;349.2.1;A. Cells of the Immune System;359.2.2;B. How Leukocytes Communicate;439.2.3;C. Lymphoid Tissues;479.2.4;D. Cellular Movement in the Immune System;539.3;Chapter 3: Innate Immunity;609.3.1;A. Non-Induced Innate Mechanisms;629.3.2;B. Induced Innate Mechanisms;639.4;Chapter 4: The B Cell Receptor: Proteins and Genes;789.4.1;A. Immunoglobulin Proteins;799.4.2;B. Immunoglobulin Genes;869.4.3;C. Antigen-Antibody Interaction;929.5;Chapter 5: B Cell Development, Activation and Effector Functions;989.5.1;A. B Cell Development: Maturation Phase;999.5.2;B. B Cell Development: Differentiation Phase;1029.5.3;C. Effector Functions of Antibodies;1139.5.4;D. Immunoglobulin Isotypes in Biological Context;1159.6;Chapter 6: The Major Histocompatibility Complex;1209.6.1;A. Overview of the Major Histocompatibility Complex;1219.6.2;B. MHC Class I and Class II Proteins;1239.6.3;C. MHC Class I and Class II Genes;1269.6.4;D. Physiology of the MHC;1299.7;Chapter 7: Antigen Processing and Presentation;1349.7.1;A. Overview of Antigen Processing and Presentation;1359.7.2;B. Exogenous Antigen Processing;1369.7.3;C. Endogenous Antigen Processing;1419.7.4;D. Cross-Presentation on MHC Class I;1439.7.5;E. Other Methods of Antigen Presentation;1449.8;Chapter 8: The T Cell Receptor: Proteins and Genes;1489.8.1;A. TCR Proteins and Associated Molecules;1499.8.2;B. TCR Genes;1529.8.3;C. TCR-Antigen Interaction;1569.9;Chapter 9: T Cell Development, Activation and Effector Functions;1609.9.1;A. T Cell Development;1619.9.2;B. T Cell Activation;1689.9.3;C. Th Cell Differentiation and Effector Function;1709.9.4;D. Tc Cell Differentiation and Effector Function;1749.9.5;E. Control of Effector T Cells;1759.9.6;F. Memory T Cells;1769.10;Chapter 10: Regulation of Immune Responses in the Periphery;1809.10.1;A. Self Tolerance of Lymphocytes in the Periphery;1819.10.2;B. Control of Lymphocyte Responses in the Periphery;1839.10.3;C. Special Tolerance Situations;1869.10.4;D. Experimental Tolerance;1889.11;Chapter 11: NK, gd T and NKT Cells;1929.11.1;A. Natural Killer (NK) Cells;1939.11.2;B. gd T Cells;1979.11.3;C. NKT Cells;2019.12;Chapter 12: Mucosal and Cutaneous Immunity;2069.12.1;A. Mucosal Immunity;2079.12.2;B. Cutaneous Immunity;21510;PART II: CLINICAL IMMUNOLOGY;22210.1;Chapter 13: Immunity to Infection;22410.1.1;A. The Nature of Pathogens and Disease;22510.1.2;B. Innate Defense against Pathogens;22510.1.3;C. Immunity to Extracellular Bacteria;22610.1.4;D. Immunity to Intracellular Bacteria;22910.1.5;E. Immunity to Viruses;23310.1.6;F. Immunity to Parasites;23910.1.7;G. Immunity to Fungi;24210.1.8;H. Prions;24310.2;Chapter 14: Vaccination;24610.2.1;A. Vaccine Design;24810.2.2;B. Types of Vaccines;25010.2.3;C. Adjuvants and Delivery Vehicles;25310.2.4;D. Prophylactic Vaccines;25310.2.5;E. The "Dark Side" of Vaccines;26010.2.6;F. Passive Immunization;26110.2.7;G. Future Directions;26110.3;Chapter 15: HIV and Acquired Immunodeficiency Syndrome;26610.3.1;A. What Is HIV?;26810.3.2;B. HIV Infection and AIDS;27110.3.3;C. Immune Responses during HIV Infection;27410.3.4;D. Host Factors Influencing the Course of HIV Infection;27510.3.5;E. Animal Models of AIDS;27610.3.6;F. HIV Vaccines;27710.3.7;G. Treatment of HIV Infection with Anti-Retroviral Drugs;27810.4;Chapter 16: Tumor Immunology;28210.4.1;A. Tumor Biology;28310.4.2;B. Tumor Antigens;28810.4.3;C. I