Beschreibung:
Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.
Articular cartilage is a highly specialized avascular connective tissue. This multidisciplinary article reviews the molecular and morphological aspects of GLUT expression and function in chondrocytes and their mesenchymal and embryonic stem cell precursors.
Articular Cartilage: Structure, Function, and Pathophysiology.- Does Arthritis Have a Nutritional Etiology?.- Metabolic Dysfunction in Arthritis.- Glucose: An Essential Metabolite and Structural Precursor for Articular Cartilage.- Mammalian Sugar Transporter Families: GLUT and SGLT.- Molecular Diversity of Facilitative Glucose Transporters in Articular Chondrocytes.- Regulation of Glucose Transport by Nonsteroidal Anti-inflammatory Drugs.- Glucose Transporters in the Intervertebral Disc.- Glucose Transporter Expression and Regulation in Embryonic and Mesenchymal Stem Cells.- Concluding Remarks.