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Prognosis of in-vitro transdermal permeation using in silico modelling
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Artikel-Nr:
9783330330887
Veröffentl:
2017
Einband:
Paperback
Erscheinungsdatum:
12.06.2017
Seiten:
80
Autor:
Bharti Sapra
Gewicht:
137 g
Format:
220x150x5 mm
Sprache:
Englisch
Beschreibung:
Authors are from Department of Pharmaceutical Sciences & Drug Research, Punjabi University, Patiala. Neha Goyal is a research scholar. Dr. Om Silakari (Assistant Prof.) and Dr. Bharti Sapra (Assistant Prof.) have published more than 30 and 22 research papers, respectively, of International repute.
Skin permeation of molecules is a multifactorial phenomenon depending on diverse types of physical, chemical and biological interactions.In vitro skin permeation studies are frequently performed for screening of molecules and drug carrier systems aimed at optimizing dermal or transdermal delivery. Mathematical models often aid directly by providing information on the rate of drug penetration through the skin and thus on dermal or system concentration of drugs. They are also helpful in analyzing experimental data, reducing the no. of experiments and translating the in vitro setting.