Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases

Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View provides an integrated outlook of the disciplines involved in the development of plant-based vaccines as well as an updated compilation of the successful developments in the field. The volume covers immunological aspects of mucosal vaccine design, molecular approaches to attain high levels of the recombinant antigens, the rationale of using bioreactor to expand plant biomass, and pharmaceutical technology approaches that have been applied to the development of plant-based vaccine formulations. Practical figures and tables are presented to facilitate reading and identification of key points. Perspectives for this field are also discussed.

Written by authorities in the field, Genetically Engineered Plants as a Source of Vaccines Against Wide Spread Diseases: An Integrated View is a comprehensive resource for researchers and students interested in plant genetics and breeding, immunology, and genetic engineering.

1. Principles of Plant-based Vaccines
Dania Olivia Govea-Alonso, Guy A. Cardineau, Sergio Rosales-Mendoza

2. Mucosal Immunology and Oral Vaccination
Ana Lilia García-Hernández, Néstor Rubio-Infante, Leticia Moreno-Fierros

3. Viral Vector-based Expression Strategies
Jorge Alberto Salazar-González, Sergio Rosales-Mendoza, Bernardo Bañuelos-Hernández

4. Modalities for Expression of Antigens in Plants: Plastid-based Expression Strategies
Jorge Alberto Salazar-González, Elizabeth Monreal-Escalante, Areli Herrera Díaz, Hans Ulrich Koop, Sergio Rosales-Mendoza

5. Seed-based Expression Strategies
Lucia Orellana Escobedo, Schuyler S. Korban, Sergio Rosales Mendoza

6. Biorreactors for Plant Biomass Production and Bioprocessing
Luz María Teresita Paz-Maldonado, José Enrique González-Ramírez

7. Influenza
Andrea Romero Maldonado, Jorge A. Salazar-González, Sergio Rosales Mendoza

8. Neglected Tropical Diseases
Elizabeth Monreal-Escalante, Sergio Rosales-Mendoza, Dania Olivia Govea-Alonso, Gladis Fragoso, Edda Sciutto

9. Human Immunodeficiency Virus
Sergio Rosales-Mendoza, Dania Olivia Govea-Alonso, Jorge Alberto Salazar-González, Schuyler S. Korban

10. Plant-based Vaccines against Hepatitis B
Tomasz Pniewski

11. Overview of Plant-made Vaccine Antigens against Toxoplasmosis
Marina Clemente

12. Allergen-specific Immunotherapy Using Seed-based Allergy Vaccines Against Pollen Allergens
Fumio Takaiwa

13. Plant-based Vaccines as a Global Vaccination Approach: Current Perspectives
Dania Olivia Govea-Alonso, Edward Rybicki, Sergio Rosales-Mendoza