Sleep Deprivation and Disease

The cognitive and behavioral implications of sleep deprivation have been noted in the medical literature for many years. In addition, emerging research continues to demonstrate the contribution of sleep deprivation to some of the most common and costly health conditions today.

Sleep Deprivation and Disease provides clinically relevant scientific information to help clinicians, public health professionals, and researchers recognize the ramifications of sleep deprivation across a broad spectrum of health topics. This timely reference covers sleep physiology, experimental approaches to sleep deprivation and measurement of its consequences, as well as health and operational consequences of sleep deprivation. Clinical challenges and areas of uncertainty are also presented in order to encourage future advancements in sleep medicine and help patients avoid the outcomes associated with the myriad causes of sleep deprivation.

I. Introduction

1.      Sleep Deprivation: Practical and Philosophical Considerations

Matt T. Bianchi

II. Sleep Physiology, Measurement, and Experimental Deprivation

2.      Functional Impact of Sleep Deprivation, Sleep Restriction, and Sleep Fragmentation

Michelle A. Short and Siobhan Banks

3.      Methods for Human Sleep Deprivation Experiments

Elizabeth B. Klerman and Matt T. Bianchi

1. Imaging Sleep and Sleep Deprivation

Thien Thanh Dang-Vu

III. Sleep and the Brain

5.      Sleep Deprivation and Neurological Disease

Matt T. Bianchi

6.      Sleep Deprivation and Psychiatric Disorders

Matt T. Bianchi and Maren Nyer

7.      Sleep Deprivation as a Therapy in Psychiatry

IV. Sleep and Medical Topics 

8.      Sleep Deprivation and Human Development

Nishi Bhopal and Umakanth Khatwa

9.      Sleep Deprivation and Pregnancy

Mihaela H. Bazalakova, Matt T. Bianchi, and Aleksandar K. Stanic

10.  Sleep Deprivation and Metabolism

Erin C. Hanlon and Kristen L. Knutson

11.  Sleep Deprivation and the Cardiovascular System

Ivan Cundrle, Jr., Andrew D. Calvin and Virend K. Somers

12.  Sleep Deprivation and Rheumatological Disease

Vivien C. Abad and Christian Guilleminault

13.  Sleep Deprivation and Pain

Akiko Okifuji and Bradford D. Hare

14.  Sleep Loss in Older Adults: Effects on Waking Performance and Sleep-Dependent Memory Consolidation with Healthy Aging and Insomnia

Edward F. Pace-Schott and Rebecca M. C. Spencer

V. Performance, Economics, and Operational Topics

1. Noise-induced Sleep Deprivation: Toward Sleeping Soundly on Noisy Nights

Jeffrey M. Ellenbogen

16.  Sleep Deprivation and Cognitive Performance

William D. S. Killgore and Mareen Weber

17.  Caffeine and Naps as Countermeasures for Sleep Loss

Yvonne Alameddine, Elizabeth B. Klerman, and Matt T. Bianchi

18.  Fatigue in the Workplace

Gregory Belenky, Amanda Lamp, Amanda Hemp, and Jennifer L. Zaslona

19.  Sleep Deprivation and Economic Burden

Tracy L. Skaer