UCL Hospitals Injectable Medicines Administration Guide

"e;I would definitely recommend this book to all staff with an interest and involvement in intravenous drug therapy."e; The Pharmaceutical Journal "e;There is no doubt that nurses will find this small book useful. It should be available for consultation in any clinical area where drugs are administered to patients by the injectable routes."e; Journal of Clinical Nursing The safe administration of injectable medicines is key to patient safety. The NPSA recognises the use of injectable medicines is a high risk activity and recommends written information about injectables to be available at the point of preparation. The UCL Hospitals Injectable Medicines Administration Guide is a practical, accessible guide covering many important aspects of administering medicines by injection. It provides clear, concise information on the preparation and administration of over 245 injectable medicines for adults, paediatrics and neonates. It is an essential resource for nurses and other healthcare professionals: it provides the key information and advice needed for the safe and effective administration of injectable medicines. The Guide s introductory section provides a concise yet comprehensive overview of injectable therapy, including the risks and benefits of IV administration, infusion devices, and pharmaceutical aspects of injectable therapy. For each drug the alphabetically tabulated monographs provide: A practical method of preparation and administration via the IV, IM and SC routes, with risk reduction in mind at every step Expert advice from the team of specialist pharmacists at UCLH to ensure safe and pragmatic use of each medicine Monitoring advice for the management of reactions that may occur during administration Y-site and syringe driver compatibility data Minimum infusion volume data for fluid restricted patients Extravasation warnings, pH, sodium content, displacement values, stability and flush data New to this edition: 40 new monographs including recently marketed, unlicensed, rarely used and specialist medicines Detailed advice for the administration of high risk medicines such as heparin, with access to UCLH s medicine related guidelines at wiley.com/go/UCLH A colour-coded NPSA risk assessment for every mode of administration for every medicine, to highlight the safest method of administration A user guide and tutorial to give new readers confidence in using and understanding the Guide Revised chapters on administration methods and devices, aseptic non-touch technique, and latex allergy Fully revised and expanded Y-site compatibility section Spiral binding to allow the book to be left open at the relevant page The Guide is also available electronically at uclhguide.com.

"I would definitely recommend this book to all staff with an interest and involvement in intravenous drug therapy."The Pharmaceutical Journal"There is no doubt that nurses will find this small book useful. It should be available for consultation in any clinical area where drugs are administered to patients by the injectable routes."Journal of Clinical NursingThe safe administration of injectable medicines is key to patient safety. The NPSA recognises the use of injectable medicines is a high risk activity and recommends written information about injectables to be available at the point of preparation.The UCL Hospitals Injectable Medicines Administration Guide is a practical, accessible guide covering many important aspects of administering medicines by injection. It provides clear, concise information on the preparation and administration of over 245 injectable medicines for adults, paediatrics and neonates. It is an essential resource for nurses and other healthcare professionals: it provides the key information and advice needed for the safe and effective administration of injectable medicines.The Guide's introductory section provides a concise yet comprehensive overview of injectable therapy, including the risks and benefits of IV administration, infusion devices, and pharmaceutical aspects of injectable therapy.For each drug the alphabetically tabulated monographs provide:* A practical method of preparation and administration via the IV, IM and SC routes, with risk reduction in mind at every step* Expert advice from the team of specialist pharmacists at UCLH to ensure safe and pragmatic use of each medicine* Monitoring advice for the management of reactions that may occur during administration* Y-site and syringe driver compatibility data* Minimum infusion volume data for fluid restricted patients* Extravasation warnings, pH, sodium content, displacement values, stability and flush dataNew to this edition:* 40 new monographs including recently marketed, unlicensed, rarely used and specialist medicines* Detailed advice for the administration of high risk medicines such as heparin, with access to UCLH's medicine related guidelines at wiley.com/go/UCLH* A colour-coded NPSA risk assessment for every mode of administration for every medicine, to highlight the safest method of administration* A user guide and tutorial to give new readers confidence in using and understanding the Guide* Revised chapters on administration methods and devices, aseptic non-touch technique, and latex allergy* Fully revised and expanded Y-site compatibility section* Spiral binding to allow the book to be left open at the relevant pageThe Guide is also available electronically at uclhguide.com.

Third edition editorial board viiiContributors ixAcknowledgements xPreface xiSection A 11 Introduction 12 Overview 22.1 Organisation of information in the Guide 22.2 Sources of information and disclaimer 33 UCLH policies 43.1 Responsibilities of professional staff at UCLH 43.2 Preparation of injectable medicines on wards, clinics and departments at UCLH 54 An overview of intravenous therapy 64.1 When is intravenous therapy appropriate? 64.2 Drug factors that influence the choice of route 74.3 Disadvantages of intravenous administration 84.4 Routes of intravenous administration 95 Factors affecting patency of intravenous sites 115.1 Factors increasing failure of intravenous sites 115.2 Factors decreasing failure of intravenous sites 115.3 Occlusion of central venous catheters 116 Methods of intravenous administration 126.1 Intravenous bolus 126.2 Intermittent intravenous infusion 136.3 Continuous intravenous infusion 136.4 Preparation and administration of intravenous medicines 146.5 Aseptic non-touch technique (ANTT) 157 Extravasation of injectables: overview and management advice 177.1 Patient factors affecting extravasation 177.2 Medicine factors affecting extravasation 177.3 Administration factors affecting extravasation 217.4 Overall risk for extravasation 217.5 Treatment of extravasation 218 Flushing cannulae, catheters and administration sets 248.1 Flushing between medicines 248.2 When not to flush 248.3 Flushing catheters and cannulae not in use 258.4 Flushing with heparin 259 Infusion pumps 269.1 Pumps used at UCLH 269.2 Volumetric pumps 269.3 Syringe pumps 269.4 Pumps for ambulatory use 279.5 Patient-controlled analgesia (PCA) pumps 279.6 Target-controlled anaesthesia (TCI or TIVA) pumps 2810 Administration of injectables in primary care 2910.1 Self-caring patients 3011 Formulation and presentation of injectables 3111.1 Medicines that require reconstitution 3111.2 Preparations in solution requiring further dilution before use 3211.3 Preparations available 'ready to use' without further dilution 3211.4 Preparations available 'ready to administer' 3212 Pharmaceutical aspects of injectable administration 3412.1 Displacement values 3412.2 Sodium content 3412.3 Drop size 3512.4 Layering 3512.5 Fluid restriction 3513 Factors influencing medicine stability and compatibility of injectable medicines 3713.1 Degradation 3713.2 Precipitation 3813.3 Binding of medicines to plastics 3813.4 Destabilisation of parenteral emulsions 3913.5 Leaching of plasticisers 3913.6 Blood and blood products 4014 Allergic reactions to injectables 4114.1 Latex allergy 4115 Compatibility of drugs in a syringe driver for subcutaneous use 4316 Risk assessment of injectables and risk reduction 4516.1 Risk assessment 4516.2 Risk reduction 4717 Useful resources 4917.1 Websites 4917.2 Further reading 50Section B 51User guide 51Monographs in alphabetical order 67Index of monographs 333