Plant Phenolics and Human Health

A collection of current knowledge of phytochemicals and health Interest in phenolic phytochemicals has increased as scientific studies indicate these compounds exhibit potential health benefits. With contributions from world leaders in this research area, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology offers an essential survey of the current knowledge on the capacity of specific micronutrients present in ordinary diets to fight disease. The coverage in this resource: Explains the presence and biochemical properties of phenolics present in fruits and vegetables, as well as in foods derived from their plant sources Provides biochemical explanations on how certain plant phenolics fight cardiovascular and neurodegenerative diseases, cancer, and other widespread pathologies Focuses on certain phenolics, e.g., flavonoids, stilbenes, and curcuminoids, and provides insights on the biochemical bases used to define their significance in the diet as well as their recommended consumption requirements and toxicity Appropriate for graduate and upper-level undergraduate courses in human and animal nutrition, basic nutritional biology, physiology, pharmacology, and other health-related disciplines, Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology serves as both an invaluable supplementary classroom text and a self-teaching guide for professionals interested in defining the association between diet and health from classical, alternative, and complementary biomedical perspectives.

A collection of current knowledge of phytochemicals andhealthInterest in phenolic phytochemicals has increased as scientificstudies indicate these compounds exhibit potential health benefits.With contributions from world leaders in this research areaPlant Phenolics and Human Health: Biochemistry, Nutrition, andPharmacology offers an essential survey of the currentknowledge on the capacity of specific micronutrients present inordinary diets to fight disease.The coverage in this resource:* Explains the presence and biochemical properties of phenolicspresent in fruits and vegetables, as well as in foods derived fromtheir plant sources* Provides biochemical explanations on how certain plant phenolicsfight cardiovascular and neurodegenerative diseases, cancer, andother widespread pathologies* Focuses on certain phenolics, e.g., flavonoids, stilbenes, andcurcuminoids, and provides insights on the biochemical bases usedto define their significance in the diet as well as theirrecommended consumption requirements and toxicityAppropriate for graduate and upper-level undergraduate coursesin human and animal nutrition, basic nutritional biologyphysiology, pharmacology, and other health-related disciplinesPlant Phenolics and Human Health: Biochemistry, Nutrition, andPharmacology serves as both an invaluable supplementaryclassroom text and a self-teaching guide for professionalsinterested in defining the association between diet and health fromclassical, alternative, and complementary biomedicalperspectives.

PREFACE.CONTRIBUTORS.1 Dietary Flavonoids and Phenolic Compounds (Indu B. Jaganathand Alan Crozier).2 Bioavailability of Flavanols and Phenolic Acids (LaurePoquet, Michael N Clifford, and Gary Williamson).3 Biochemical Actions of Plant Phenolics Compounds:Thermodynamic and Kinetic Aspects (Cesar G. Fraga, GulcinSagdicoglu Celep, and Monica Galleano).4 Flavonoids-Membrane Interactions: Consequences forBiological Actions (Sandra V. Verstraeten, Cesar G. Fraga, andPatricia I. Oteiza).5 The Biochemistry Behind the Potential CardiovascularProtection by Dietary Flavonoids (Wai Mun Loke, Jonathan M.Hodgson, and Kevin D. Croft).6 Dietary Flavanols: Biochemical Basis of Short-Term andLonger-Term Vascular Responses (Tankred Schewe, Yvonne SteffenElisabeth Kravets and Helmut Sies).7 Green Tea Catechins: Anticancer Effects and Molecular Targets(Naghma Khan and Hasan Mukhtar).8 Flavonols: Metabolism, Bioavailability, and Health Impacts(Junji Terao).9 Flavonols: Biochemistry Behind Cardiovascular Effects(Francisco Pérez-Vizcai´no and JuanDuarte).10 Metabolism, Bioavailability, and Analysis of DietaryIsoflavones (Adrian A. Franke, Brunhild M. Halm, Kerry Kakazuand Xingnan Li).11 Phytoestrogens Up-regulate Antioxidant Genes (ConsueloBorrás and Jose Viña).12 Dietary Isoflavones: Cardiovascular Actions and Activation ofCellular Signalling Pathways (Richard C. M. Siow and Giovanni E.Mann).13 Bioavailability and Metabolism of Resveratrol (CristinaAndres-Lacueva, Mireia Urpi-Sarda, Raul Zamora-Ros, and Rosa M.Lamuela-Raventos).14 Resveratrol: Biochemistry and Functions (Samarjit DasHannah R. Vasanthi, and Dipak K. Das).15 Resveratrol: The Biochemistry Behind its Anticancer Effects(Joydeb K. Kundu and Young-Joon Surh).16 Curcumin: The Biochemistry Behind Its Anticancer Effects(Preetha Anand, Ajaikumar B. Kunnumakkara, and Bharat B.Aggarwal).17 Plant Phenolic Compounds: Modulation of CytoprotectiveEnzymes and Nrf2/ARE Signaling (Siwang Yu, Ka Lung Cheung, WengeLi and Ah-Ng Kong).18 Phenolics in Aging and Neurodegenerative Disorders(Vittorio Calabrese, Marzia Perluigi, Carolin CorneliusRaffaella Coccia, Fabio Di Domenico, Giovanni Pennisi, Chiara Ciniand Albena T. Dinkova-Kostova).19 Natural Phenolics and Metal Metabolism in NeurodegenerativeDiseases (Baolu Zhao).20 Epidemiology behind Fruit and Vegetable Consumption andCancer Risk with Focus on Flavonoids (Marta Rossi, Eva NegriCristina Bosetti, Claudio Pelucchi, and Carlo La Vecchia).21 Phenylpropanoid Metabolism in Plants: BiochemistryFunctional Biology, and Metabolic Engineering (Alberto B.Landolino and Douglas R. Cook).INDEX.