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Catalytic Antibodies
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Artikel-Nr:
9780470514115
Veröffentl:
2008
Einband:
E-Book
Seiten:
270
Autor:
Derek J. Chadwick
eBook Typ:
PDF
eBook Format:
Reflowable E-Book
Kopierschutz:
Adobe DRM [Hard-DRM]
Sprache:
Englisch
Beschreibung:
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound ramifications for chemistry. In addition to their potential commercial applications as catalysts for reactions, for which there are no known enzymes, antibodies promise to provide valuable insight into the detailed mechanisms of biological catalysis and organic chemistry.
Partial table of contents:A Catalytic Antibody Uses a Multistep Kinetic Sequence (S.Benkovic, et al.).Nuclear Magnetic Resonance Studies of Antibody-AntigenInteractions (Y. Arata).Approaches to the Design of Semisynthetic Metal-DependentCatalytic Antibodies (G. Nakayama & P. Schultz).Catalytic Antibodies: Contributions from Engineering andExpression in Escherichia coli (A. Plückthun & J.Stadlmüller).Screening Combinatorial Antibody Libraries for Catalytic AcylTransfer Reactions (L. Sastry, et al.).Antibody Catalysis of Carbon-Carbon Bond Formation (D.Hilvert).Catalytic Antibodies: A New Window on Protein Chemistry (C.Suckling, et al.).Tritylase Antibodies (B. Iverson, et al.).Index of Contributors.Subject Index.