Biochemical Thermodynamics

Navigate the complexities of biochemical thermodynamics with Mathematica(r) Chemical reactions are studied under the constraints of constant temperature and constant pressure; biochemical reactions are studied under the additional constraints of pH and, perhaps, pMg or free concentrations of other metal ions. As more intensive variables are specified, more thermodynamic properties of a system are defined, and the equations that represent thermodynamic properties as a function of independent variables become more complicated. This sequel to Robert Alberty's popular Thermodynamics of Biochemical Reactions describes how researchers will find Mathematica(r) a simple and elegant tool, which makes it possible to perform complex calculations that would previously have been impractical. Biochemical Thermodynamics: Applications of Mathematica(r) provides a comprehensive and rigorous treatment of biochemical thermodynamics using Mathematica(r) to practically resolve thermodynamic issues. Topics covered include: * Thermodynamics of the dissociation of weak acids * Apparent equilibrium constants * Biochemical reactions at specified temperatures and various pHs * Uses of matrices in biochemical thermodynamics * Oxidoreductase, transferase, hydrolase, and lyase reactions * Reactions at 298.15K * Thermodynamics of the binding of ligands by proteins * Calorimetry of biochemical reactions Because Mathematica(r) allows the intermingling of text and calculations, this book has been written in Mathematica(r) and includes a CD-ROM containing the entire book along with macros that help scientists and engineers solve their particular problems.

Navigate the complexities of biochemical thermodynamics withMathematica(r)Chemical reactions are studied under the constraints of constanttemperature and constant pressure; biochemical reactions arestudied under the additional constraints of pH and, perhaps, pMg orfree concentrations of other metal ions. As more intensivevariables are specified, more thermodynamic properties of a systemare defined, and the equations that represent thermodynamicproperties as a function of independent variables become morecomplicated.This sequel to Robert Alberty's popular Thermodynamics ofBiochemical Reactions describes how researchers will findMathematica(r) a simple and elegant tool, which makes it possibleto perform complex calculations that would previously have beenimpractical. Biochemical Thermodynamics: Applications ofMathematica(r) provides a comprehensive and rigorous treatment ofbiochemical thermodynamics using Mathematica(r) to practicallyresolve thermodynamic issues.Topics covered include:* Thermodynamics of the dissociation of weak acids* Apparent equilibrium constants* Biochemical reactions at specified temperatures and variouspHs* Uses of matrices in biochemical thermodynamics* Oxidoreductase, transferase, hydrolase, and lyase reactions* Reactions at 298.15K* Thermodynamics of the binding of ligands by proteins* Calorimetry of biochemical reactionsBecause Mathematica(r) allows the intermingling of text andcalculations, this book has been written in Mathematica(r) andincludes a CD-ROM containing the entire book along with macros thathelp scientists and engineers solve their particular problems.

Preface.Chapter 1: Thermodynamics of the Dissociation of Weak Acids.Chapter 2: Introduction to Apparent Equilibrium Constants.Chapter 3: Biochemical Reactions at Specified Temperature andVarious pHs.Chapter 4: Biochemical Reactions at Various pHs and VariousTemperatures.Chapter 5: Biochemical Reactions at Various pHs, pMgs, andVarious Temperatures.Chapter 6: Development of a Database on Species.Chapter 7: Uses of Matrices in Biochemical Thermodynamics.Chapter 8: Oxidoreductase Reactions (Class 1) at 298.15 K.Chapter 9: Transferase Reactions (Class 2) at 298.15 K.Chapter 10: Hydrolase Reactions (Class 3) at 298.15 K.Chapter 11: Lyase Reactions (Class 4), Isomerase Reactions(Class 5), and Ligase Reactions (Class 6) at 298.15 K.Chapter 12: Survey of Reactions at 298.15 K.Chapter 13: Survey of Reactions at Various Temperatures.Chapter 14: Thermodynamics of th Binding of Ligands byProteins.Chapter 15: Calorimetry of Biochemical Reactions.Appendix.1. BasicBiochemData3.nb.2. Tables of Transformed Thermodynamic Properties.3. Glossary of Names of Reactants.4. Glossary of Symbols for Thermodynamic Properties.5. List of Mathemutica Programs.6. Sources of Biochemical Thermodynamic Information on theWeb.Index.