Fundamentals of Toxicology
Beschreibung:
Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding.
The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.
Unit I
Chapter 1. Introduction and historical background
Chapter 2. Definitions and scope of toxicology
Chapter 3. Classification of poisons/toxicants
Chapter 4. Factors affecting toxicity
Chapter 5. Natural laws concerning toxicology
Chapter 6. Hazard and risk assessment
Unit II
Chapter 7. Absorption, distribution, and excretion of toxicants
Chapter 8. Biotransformation
Chapter 9. Principles and basic concepts of toxicokinetics
Unit III
Chapter 10. Toxicological testing: Genesis
Chapter 11. Toxicological testing: In vitro models
Chapter 12. Toxicological testing: In vivo systems
Chapter 13. Genotoxicity
Chapter 14. Preclinical toxicological investigations of pharmaceutical products
Chapter 15. Preclinical safety evaluation of biotechnology-derived products
Chapter 16. Preclinical regulatory toxicology for biomaterials and medical devices
Unit IV
Chapter 17. Toxic effects of pesticides (agrochemicals)
Chapter 18. Toxic effects of metals
Chapter 19. Toxic effects of nonmetallics
Chapter 20. Neurotoxic agents
Chapter 21. Toxic effects of cardiac poisons
Chapter 22. Toxic effects of asphyxiants
Chapter 23. Toxic effects of caustics (corrosives)
Chapter 24. Drug toxicity, dependence, and abuse
Chapter 25. Toxic effects of domestic chemicals
Chapter 26. Toxic effects of poisonous plants
Chapter 27. Poisonous foods and food poisoning
Chapter 28. Poisons of animal origin
Chapter 29. Chemical food poisoning
Chapter 30. Health effects of radioactive materials
Unit V
Chapter 31. Basic concepts of forensic toxicology
Chapter 32. Applications in toxicology
Chapter 33. Clinical toxicology
Chapter 34. Treatment of poisoning